Abstract

This research project aims to explore and understand the mechanisms associated with the pathogenesis of BD through specific aims: Develop a standard analytic pipeline for preprocessing and analyzing BCNs using rs-fMRI data and clinical and demographic records from the Adolescent Brain Cognitive Development (ABCD) study. This will allow us to quantitatively understand the cognitive development of adolescents with BD, ultimately improving diagnosis and treatment for this population. The goal of this research project is to address critical issues in the preprocessing and analysis of rs-fMRI data to enhance our comprehension of BD, develop more accurate methods for diagnosis and treatment, and reduce the public health impact of this disorder.

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Article History
  • Submitted: November 30, 2025
  • Published: November 23, 2025